Skip to main content

Agentic Automation Manager

Job ID 370662 Date posted 11/14/2025
  • Rochester, MN
  • Remote: Yes
Apply Now

Not ready to apply? Join our talent community


Overview

Be challenged to deliver innovative solutions that will change health care.

Mayo Clinic’s tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies.

Some examples of our major initiatives are:

  • Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems
  • Transforming the practice by applying data science techniques to discover new approaches to health care delivery
  • Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support

This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first.

Job Description

CityRochester

StateMN

RemoteYES

DepartmentArtificial Intelligence & Informatics

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.


Responsibilities

Job Summary

The principal enterprise architect of agentic automation leads the day-to-day operating framework that scales agentic automation across the enterprise. The role transforms strategy into execution by standardizing intake and triage, building guardrails, expanding federated capabilities across DMCs/departments, and stewarding the Citizen Development Program. Success looks like predictable delivery, measurable value (ROI/KPIs), and a continuously improving “push-led” pipeline that advances enterprise goals rather than relying primarily on crowdsourced intake.

Key Responsibilities

Leadership & Strategy

  • Operate the Agentic Operations & Enablement function that underpins the Enterprise Automation program.
  • Translate enterprise automation and agentic strategy into standard processes, playbooks, and delivery cadences.
  • Drive a push-oriented pipeline aligned to business objectives and ROI; supplement with high-quality pull intake when appropriate.
  • Stay current on RPA, LLMs, and agentic orchestration trends to inform roadmaps and operating methods.

Program Development

  • Define program KPIs and balanced scorecards (e.g., cycle time, accuracy, adoption, deflection, cost savings, risk reduction, satisfaction).
  • Build value models and ROI calculators for agentic use cases; maintain benefit realization tracking post-go-live.
  • Standardize and optimize operating practices across the portfolio (intake → triage → discovery → design → build → test → deploy → run).
  • Establish and maintain controls and guardrails for security, compliance, data access, and safe use of autonomous/semi-autonomous agents.
  • Grow and support federated automation teams across DMCs/departments with shared standards, reusable components, and coaching.
  • Expand and steward the Citizen Development Program with curricula, certification paths, governance tiers, and reusable “agent patterns.”

Advocacy & Education

  • Advocate for RPA/AI/agentic solutions through enablement briefings, roadshows, and community forums.
  • Lead top-down (executive- and service-line-driven) and bottoms-up (frontline- and citizen-led) ideation streams, curating into a single prioritized pipeline.
  • Build trust and credibility with internal and external stakeholders (vendors, ecosystem partners, advisory groups) to accelerate safe, scalable adoption.

Team & Relationship Management

  • Lead a small cross-functional team (analysts, coordinators, federated contributors) to identify and qualify automation opportunities.
  • Provide mentorship on process assessment, agentic design patterns, documentation quality, and delivery best practices.
  • Manage iterative stakeholder engagement: schedule and run ideation sessions, discovery workshops, and executive updates.
  • Conduct high-level process assessments to generate pipeline and perform use-case evaluations with clear acceptance criteria.

Program Coordination & Delivery

  • Coordinate with Automation Hub leadership on portfolio progress, dependencies, and risk/issue management.
  • Oversee administrative facets: vendor relationships, SOW coordination, licensing inventories, budget tracking, and resource plans.
  • Create detailed project plans, RAID logs, and milestone trackers; maintain dashboards for status, risks, KPIs, and value realization.
  • Measure project performance with appropriate tools and techniques; publish recurring reports and escalate issues with actionable options.


Qualifications

Qualifications

  • Experience: 5–8 years in automation operations, business process management, digital transformation, or PMO/enablement roles.
  • Technical Acumen: Familiarity with RPA platforms (e.g., UiPath/Power Automate), LLM-driven/agentic orchestration concepts, and enterprise integration basics.
  • Operational Excellence: Proven ability to standardize processes, manage intake/triage, and run measurement/benefits realization.
  • Stakeholder Skills: Strong communication, facilitation, and relationship management across clinical/operational/IT stakeholders and vendor partners.
  • Governance Mindset: Comfort with controls, compliance, and change management for autonomous/semi-autonomous systems.

Education & Experience

  • Bachelor’s degree in Information Systems, Computer Science, Industrial Engineering, Business, or related field; master’s preferred.
  • Demonstrated experience building or scaling an automation enablement function, PMO, or citizen development program.
  • Portfolio evidence of KPI design, ROI modeling, and value tracking for automation initiatives.

Competencies

  • Agentic Literacy: Understand when to apply autonomous vs. human-in-the-loop patterns and how to design guardrails.
  • Program Rigor: Habit of codifying standards, templates, and reusable assets for predictable outcomes.
  • Value Orientation: Bias toward measurable results, transparent metrics, and credible storytelling of impact.
  • Change Leadership: Able to coach teams, reduce friction, and grow confidence in working with digital agents.


Exemption Status

Exempt

Compensation Detail

Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Hours/Pay Period

80/pay period

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.


Recruiter

Adriana Semko
Apply Now

Career Path

Discover unlimited opportunities. Your IT career may start as a Help Desk Specialist or Work Station Technician, an intern, or entry-level Analyst/Programmer and develop into a mid- or senior-level technical position. You may choose to grow laterally as a technical expert, learning and supporting many different aspects of IT services. Or you may choose to become part of the leadership team.

  • Applications
  • Business Relationship Management
  • Enterprise Infrastructure
  • Enterprise Architecture
  • Information
    Security
  • Management
  • Project Management and Systems Analysis
  • Quality
    Assurance

The Life Changers

  • When you choose an IT career with Mayo Clinic you will have an opportunity to engage with new and innovative solutions which will improve quality of life and patient outcomes. You will partner with brilliant Physicians and Scientists to help drive translational medicine in a fast-paced environment where creativity, energy, and dedication will result in success.”

    Marie Koctecki
    Senior Manager, IT Service Delivery
  • Over the span of my career, I have worked in multiple divisions across IT and have now advanced to a Service Delivery Manager role, managing a Project Management Office (PMO). The opportunities within the department of IT are vast. I have been able to gain my Project Management Professional (PMP) certification as well as my Certified Scrum Master (CSM) certification while at Mayo Clinic.”

    Betty Hutchins
    Manager, IT Service Delivery
  • I appreciate the breadth of career paths within IT and the ability to branch out and diversify my professional expertise while remaining with Mayo Clinic. The diverse backgrounds and depth of expertise of my coworkers is an attribute of Mayo’s unique culture; I enjoy the opportunity to work with so many world-renowned experts and thought leaders across a wide array of professions.”

    Samanthie Epps
    Manager, IT Speciality Systems

Join our talent community.

From roles that are right for you to new opportunities, keep up-to-date on job openings and more.

Join our talent community.

From roles that are right for you to new opportunities, keep up-to-date on job openings and more.

Interested InPlease select a category or location option. Click “Add” to create your job alert.

By signing up, I acknowledge I have read the Mayo Clinic privacy policy , and I wish to receive email and SMS communications. I understand I can opt-out from receiving email and SMS communications at any time.

Already a Member

News

  • Image of Lab

    Mayo Clinic Laboratories uses enhanced technology to safeguard patient specimens

    To improve specimen safety and tracking, Mayo Clinic Laboratories is using an enhanced form of radio-frequency...

  • Virtual Reality

    Mayo Clinic and vMocion Introduce Technology which Creates the Sensation of Motion, Transforming Vir

    Mayo Clinic and vMocion, LLC, an entertainment technology company, today announced it is making...

Jobs for you

You have no Recently Viewed Jobs. View all available opportunities.

Equal opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or disability status. Learn more about "EEO is the Law." Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Wage and Hour Divisions FMLA poster

Employee Polygraph Protection Act Rights Poster

Mayo Equal Employment Opportunity Policy 2025

Reasonable accommodations

Mayo Clinic provides reasonable accommodations to individuals with disabilities to increase opportunities and eliminate barriers to employment.  If you need a reasonable accommodation in the application process; to access job postings, to apply for a job, for a job interview, for pre-employment testing, or with the onboarding process, please contact HR Connect at 507-266-0440 or  888-266-0440.

Job offers

Job offers are contingent upon successful completion of a post offer placement assessment including a urine drug screen, immunization review and tuberculin (TB) skin testing, if applicable.

Recruitment Fraud

Learn more about recruitment fraud and job scams

Advertising

Mayo Clinic is a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.

Advertising and sponsorship policy | Advertising and sponsorship opportunities

Reprint permissions

A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.

Terms and Conditions | Privacy Policy | Notice of Privacy Practices | Notice of Nondiscrimination

© 1998-2025 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.

Top