Research Fellow - Cellular and Molecular GI Physiology

Gastroenterology & Hepatology
Position description
A motivated early career Molecular and Cellular Physiologist who is looking for a path to independence is sought for an NIH-funded post-doctoral fellowship connecting basic mechanisms of cellular excitability to disease.

The Enteric Neuroscience Program (ENSP) at Mayo Clinic in Rochester, Minnesota is an established and uniquely diverse group of NIH-supported investigators. The program includes laboratories focused on Gastrointestinal Mechano-transduction (PI Beyder) and Cellular and Molecular Gastrointestinal Physiology (PIs Gibbons and Farrugia). Overall the ENSP at Mayo Clinic has a broad interest in using cutting edge techniques to understand cellular and molecular mechanisms of gastrointestinal function in health and disease. The latest studies from the group have contributed high impact publications to the multiple recent discoveries related to the gastrointestinal tract, probably the most important organ in your body.

The goals of this NIH-supported project are to determine the mechanisms and roles of mechanotransduction in excitability of cells and cellular networks in the gastrointestinal tract. The studies involve next generation sequencing, epigenomics, chromatin immuno-precipitation (ChIP) and cutting edge transgenic models to manipulate and image gastrointestinal physiology in animal models of disease as well as in patient tissues. The successful candidate should most importantly be motivated, and preferably have a background in molecular and cellular biology, genome editing (CRISPR-based) techniques and experience in applying bioinformatics analysis to proteomic, genomic and transcriptomic data. Experience in gastrointestinal physiology is desired but not necessary.

A clearly defined career path and evidence of an ability and interest in obtaining independent funding would be a great asset for any applicant.

For more details contact: Simon J Gibbons PhD (@sgibbonsmn) or Arthur Beyder MD, PhD (@BeyderLab) or email: including a statement of your career goals and interests and an NIH style bibliography.

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic. Please attach the following required documents at the time of application.
  • Current curriculum vitae and bibliography
  • Three letters of recommendation, signed, on letterhead, describing:
    • Relationship to the applicant.
    • Past work/academic performance.
    • Work qualities/personal conduct.
    • Overall assessment of potential for success in research environment.
  • Doctoral degree certification, if applicable:
    • Original or notarized copy of diploma or final transcript issued by school (English translation required).
800146; J2WRTP
Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.
Additional qualifications

Benefits eligible
Full Time
Site description
Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.
Postdoc & Temporary Research
Career profile
Post Doctoral Research
Gastroenterology & Hepatology, Research
Job posting number
Saundra Wilson