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Senior Information Security Engineer - IS Mod

Job ID 387286 Date posted 07/29/2026 Job Expiration Date 08/07/2026
  • Rochester, MN
  • Full Time
  • Remote: No
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Overview

Be challenged to deliver innovative solutions that will change health care.

Mayo Clinic’s tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies.

Some examples of our major initiatives are:

  • Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems
  • Transforming the practice by applying data science techniques to discover new approaches to health care delivery
  • Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support

This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first.

Job Description

CityRochester

StateMN

RemoteNO

DepartmentInformation Security


Responsibilities

This Senior Information Security Engineer serves as the dedicated security design and oversight lead for Enterprise Network Segmentation within the Information Protection – Network Security (IP-NS) team, ensuring segmentation controls are architected to appropriately align with the risk profile of the assets they protect across a large, regulated healthcare environment. A strong background in network segmentation is required, including proven experience designing risk-based segmentation strategies and defining policy intent for high-risk assets. This role is a critical technical authority who partners with Product Owners, the Network Security Architect, network engineering teams, and enterprise risk stakeholders to translate asset criticality and threat modeling into control requirements.  It will also validate implemented policy meets design intent; provide continued oversight of segmentation controls and drift; contribute to Tier 3 incident response; and support executive reporting on risk-reduction outcomes aligned to security control objectives.  Familiarity with security monitoring, incident response, vulnerability management, and security automation is highly desirable.  Ability to operate effectively in a hybrid work environment, including participation in on-site work-related events, team collaboration sessions, and key organizational activities as required.

This is a hybrid position and the incumbent must live within 100 miles of a Mayo Clinic campus.

Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM.



Qualifications

Bachelor’s degree in applicable field plus five (5) years of relevant experience.  Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, engineering, or a related field.

Master’s degree in applicable field plus four (4) years of relevant experience preferred.  Pertinent fields of study and experience include, but are not limited to, information security, computer science, information systems, engineering, or a related field.

One or more of the following certifications (or equivalent) are required at time of hire: CISSP, CISM, GSEC, OSCP.



Exemption Status

Exempt

Compensation Detail

$134,347.20 - $194,750.40/ year

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Monday - Friday, 8am - 5pm

International Assignment

No

Recruiter

Ted Keefe
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Career Path

Discover unlimited opportunities. Your IT career may start as a Help Desk Specialist or Work Station Technician, an intern, or entry-level Analyst/Programmer and develop into a mid- or senior-level technical position. You may choose to grow laterally as a technical expert, learning and supporting many different aspects of IT services. Or you may choose to become part of the leadership team.

  • Applications
  • Business Relationship Management
  • Enterprise Infrastructure
  • Enterprise Architecture
  • Information
    Security
  • Management
  • Project Management and Systems Analysis
  • Quality
    Assurance

The Life Changers

  • When you choose an IT career with Mayo Clinic you will have an opportunity to engage with new and innovative solutions which will improve quality of life and patient outcomes. You will partner with brilliant Physicians and Scientists to help drive translational medicine in a fast-paced environment where creativity, energy, and dedication will result in success.”

    Marie Koctecki
    Senior Manager, IT Service Delivery
  • Over the span of my career, I have worked in multiple divisions across IT and have now advanced to a Service Delivery Manager role, managing a Project Management Office (PMO). The opportunities within the department of IT are vast. I have been able to gain my Project Management Professional (PMP) certification as well as my Certified Scrum Master (CSM) certification while at Mayo Clinic.”

    Betty Hutchins
    Manager, IT Service Delivery
  • I appreciate the breadth of career paths within IT and the ability to branch out and diversify my professional expertise while remaining with Mayo Clinic. The diverse backgrounds and depth of expertise of my coworkers is an attribute of Mayo’s unique culture; I enjoy the opportunity to work with so many world-renowned experts and thought leaders across a wide array of professions.”

    Samanthie Epps
    Manager, IT Speciality Systems

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