The Bose Lab (Faculty Page: Dr. Suman Bose) at Mayo Clinic Arizona invites applications for multiple Postdoctoral Fellow positions in Biomedical Engineering, with a focus on regenerative medicine, cellular engineering, and synthetic biology. Our lab develops next-generation cellular and molecular therapies for liver regeneration, whole organ engineering, and cell-based drug delivery. This role offers an exciting opportunity to engage in translational research within a multidisciplinary team that integrates biology, engineering, and clinical science.

We seek candidates with expertise in one or more of the following areas:

1) Regenerative Medicine and Cellular Therapies

• Previous experience with in vivo testing in animal models
• Experience in animal models of liver fibrosis (preferred but not required)
• Mammalian cell culture
• Development of cellular therapies (MSC, iPSC, CAR-T, etc.) for tissue regeneration
• Background in transplantation research desirable

2) Cellular Engineering and Synthetic Biology

• Extensive experience with mammalian cell culture
• Proficiency in end-to-end genetic engineering workflows, including plasmid and vector design, cloning, transfection/transduction, selection, and establishment of engineered mammalian cell lines.
• Genome-wide CRISPR screens
• Design and implementation of synthetic gene circuits for therapeutic applications
• Prior experience with in vivo testing strongly preferred

Key Responsibilities

• Develop innovative therapies for liver regeneration
• Conduct animal studies to evaluate in vivo safety and efficacy
• Engineer mammalian cell lines for controlled production of therapeutic molecules
• Collaborate with a multidisciplinary team of experts in engineering, immunology, biology, pharmacology, and clinical sciences
• Contribute to grant writing and help achieve funding milestones
• Publish high-impact research in peer-reviewed journals and present at international conferences

To apply, please submit the application with below materials.

1. Cover letter describing your research experience, motivation, and fit for this role. Please indicate the specific area of expertise (Regenerative Medicine or Cellular Engineering).
2. CV including a list of publications
3. Contact information for three professional references
4. Relevant publications or preprints (optional but encouraged)

• PhD in Biomedical Engineering, Biology, Pharmacology, or a related field (recent graduates encouraged to apply)
• Strong track record in regenerative medicine or cellular engineering, with at least one first-author publication in a peer-reviewed journal
• Prior experience in animal studies and mammalian cell culture required
• Ability to work independently while thriving in a collaborative, fast-paced environment
• Excellent organizational skills and evidence of high-quality research output
• Strong written and verbal communication skills