The Mayo Clinic Department of Neuroscience is recruiting an outstanding early- to mid-career scientist (PhD, MD/PhD, MD or equivalent) with neurotherapeutic research focus and expertise in biotechnology and complex neurologic diseases, including neurodegenerative dementias, movement, neurovascular, neuroimmune disorders and aging. This individual is expected to establish a robust research program utilizing molecular therapeutic tools to develop therapeutic interventions for neurodegenerative and other complex neurologic disease processes and to take full advantage of the Center for Regenerative Biotherapeutics, Mayo Clinic Innovation Exchange, and Department of Neuroscience research programs at Mayo Clinic.

Candidates are expected to develop a robust nucleotide, small molecule, gene-therapy and/or other modalities-based therapeutic programs. They would provide resources and establish platforms including but not limited to therapeutic design, screening and applications to support existing neuroscience programs for the development of novel therapeutic interventions. In addition to supporting and collaborating with research scientists within the Neuroscience department, the candidate is expected to establish an independent, extramurally funded research program. Finally, the candidate is expected to participate in education and institutional administrative activities. Current or prior experience in Industry or Biotechnology is preferred. 

THE DEPARTMENT OF NEUROSCIENCE is internationally recognized for academic excellence with a specific focus on understanding the etiology and developing diagnostic and treatment methods for complex neurologic diseases, including neurodegenerative dementias, movement, neurovascular, neuroimmune disorders and aging. The Department spans all Mayo Clinic sites and includes 28 primary faculty members, 62 allied health staff, 126 postdoctoral associates, and 36 doctoral students. Scientists within the neuroscience department have strong expertise in neurogenomics, neuropathology, disease modeling, molecular and cell biology, immunity, and experimental therapeutics. The Department faculty play key roles in the Alzheimer’s Disease Research Center and other large-scale NIH-funded consortia.  In 2023, the Department of Neuroscience received over $50M in funding, majority of which was from federal grants. Our faculty holds leadership roles on major NIH and foundation programs including but not limited to AMP-AD, CLEAR-AD, Dementia with Lewy Bodies Consortium, Tau Center without walls.

Breakthrough innovation does not just occur on its own. It requires focus, hard work, and being connected to the right people, places, and resources to make it all happen. The Mayo Clinic Innovation Exchange is a platform that supports all these needs, bringing health care entrepreneurs, startups, and industry experts together to bring breakthrough innovations to market. Currently, the Mayo Clinic Innovation Exchange supports over 90 start-ups, all for one shared mission—to benefit patients.

Highlights of Mayo Clinic Research Enterprise:

• Over 5,000 research personnel, including 317 faculty level research investigators and 909 physicians who are actively involved in research.
• 10,505 peer-reviewed papers were published in 2023.
• Investments in research each year that result in hundreds of new clinical trials. In 2023, the institution received over $689 million in extramural research awards supplemented with over $446 million of institutional support.
• Nearly 10,000 active studies involving human participants in progress. More than 6,050 research grants and contracts.
• State-of-the art laboratories and shared resource facilities, including those for microscopy and imaging, cell and molecular biology, animal models, production of iPS cells and clinical grade MSCs, biomedical engineering and mathematics, materials testing, a Medical Genomics Facility, a Mouse Modeling Facility, Molecular and Microscopic Core Facilities, and unique Human Disease Tissue Banks.
• Over 420,000 square feet of research laboratory space includes several robotic freezers capable of storing 3.5 million DNA samples.
• Mayo Clinic supports innovation and has a wealth of resources available – including an integrated health record and collaboration with top specialists.
• Mayo Clinic Brain Bank housed within the Department of Neuroscience and including 11,000 unique brains with neuropathologic characterizations from donors with neurodegenerative diseases and other conditions.

About Mayo Clinic

Mayo Clinic is top ranked in more specialties than any other care provider according to U.S. News & World Report. With a 73,000-person workforce, Mayo Clinic cares for more than 1.3 million people each year with serious or complex illnesses from all 50 U.S. states and 130 countries. Mayo Clinic is the largest not-for-profit, multidisciplinary academic medical center in the world with over 4,000 physicians and scientists in an integrated multi-campus system spanning the globe. 

The unified mission at Mayo Clinic is to provide the best patient care, backed by our expertise and supported by innovation in education, research and practice, to bring hope and healing in times of need. We embrace collegial relationships among campuses (Arizona, Florida and Minnesota) allowing for best practices and innovation to help solve the most serious complex medical challenges-one patient at a time.

As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in a highly competitive compensation package with substantial long-term institutional and departmental support for salary, personnel, equipment, and travel as well as a competitive startup package all designed to ensure immediate and continued success. Additional benefits for faculty at Mayo Clinic include intramural funding opportunities for research and innovation. We provide an outstanding, comprehensive benefits package that includes plenty of options for medical, dental and vision care; flexible spending accounts; life insurance; short- and long-term disability coverage; travel allowance; generous time away; and more! We are proud to be among the few U.S. companies to provide a pension benefit at no cost to employees plus you can add the Mayo 403(b) plan which features an employer match.

The successful candidate will have a PhD, MD/PhD, MD (or equivalent degree) with a sustained track record of success in extramural funding (current R01 or R01-equivalent funding as PI), publications, and collaborations with scientists and physicians. Experience in Industry and Biotechnology is preferred. Appointment and academic rank will be determined based on the candidate’s qualifications. Successful candidates will be at the level of Associate or full tenured Professor.

Applications should include a full CV/Bibliography, statement of research interests, statement of contributions to equity/inclusion/diversity, and the names/contact information of five references. 

As an Affirmative Action and Equal Opportunity Employer, Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams.  Reasonable accommodations to access job openings or to apply for a job are available.