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Senior Software Engineer - AI/ML

Job ID 361604 Date posted 06/25/2025 Job Expiration Date 07/07/2025
  • Rochester, MN
  • Full Time
  • Remote: Yes
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Overview

Be challenged to deliver innovative solutions that will change health care.

Mayo Clinic’s tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies.

Some examples of our major initiatives are:

  • Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems
  • Transforming the practice by applying data science techniques to discover new approaches to health care delivery
  • Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support

This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first.

Job Description

CityRochester

StateMN

RemoteYES

DepartmentInformation Technology

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.


Responsibilities

It is an exciting time at Mayo Clinic, as we are building the most trusted generative AI and LLM-based solutions to empower our staff, improve our practice and transform healthcare. To accelerate our generative AI strategy, we are forming a cross functional team of technical experts. This team will be responsible for:

  • Building the most trusted generative AI and automation solutions to benefit patients worldwide.
  • Providing temporary tiger-team efforts to accelerate key initiatives.
  • Expanding the organization’s understanding of LLM technology through:
    • Development of best practices, knowledge assets, and code examples to accelerate the efforts of others.
    • Execution of technical proofs of concept and exploration
  • Providing consultations, presentations, and sharing of knowledge across Mayo Clinic to technical and non-technical audiences
  • Providing guidance across the Generative AI program workstreams as technical experts

This is a full-time, remote position.  Incumbent must live within the United States.  Mayo Clinic will not sponsor or transfer visas for this position including F1 OPT STEM. 

Position Responsibilities: 

  • Leverage advanced machine learning techniques, including deep learning, natural language processing, computer vision and large language models, to lead the design, development, rigorous evaluation, and deployment of foundational AI models for healthcare applications. The initial focus will be AI models used within Cancer research & practice domain. 
  • Apply a scientific mindset and strong experimental rigor to the full spectrum of the AI lifecycle, from ideation and rapid prototyping to robust production deployment.
  • Leverage advanced techniques in AI/ML to analyze vast amounts of diverse healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet complex clinical needs and integrate smoothly into clinical processes. Special emphasis will be placed on multi-modal fusion techniques to derive deeper insights across various data sources.
  • Collaborate with multidisciplinary teams, including clinical subject matter experts and researchers, to support the engineering and implementation of cutting-edge AI/ML solutions.
  • Develop robust machine learning pipelines to support production processes, ensuring data integrity and setting new benchmarks for safety, effectiveness, and fairness in clinical settings.
  • Facilitate consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools, frameworks, and associated MLOps pipelines.
  • Contribute to implementing the best practices and standards for AI model development, evaluation methodologies, and deployment within a regulated healthcare environment.
  • Provide mentorship, guidance, and technical leadership to junior engineers within the AI enablement team, fostering a culture of innovation and scientific inquiry.
  • Provide consultative services on areas of expertise to clinical work units or AI product teams, offering deep technical insights and strategic advice to address complex business problems. Serve as an expert advisor on all AI model aspects, collaborating closely with senior data scientists.
  • Contribute to developing new AI methods and technologies that can advance the state-of-the-art in healthcare AI, including exploring novel architectures and data fusion strategies.

A Codility Test may be required as part of the candidate selection process.



Qualifications

Required qualifications for this position include: Bachelor's Degree in Computer Science/Engineering or related field with 5 years of experience as noted below; OR an Associate’s degree in Computer/Science/Engineering or related field with 7 years of experience. 

Have in-depth knowledge of software engineering with experience coding applications or services in a high-level language (C, C++, Golang, Java, C# etc.) and a basic knowledge of related fields.
Demonstrated problem solving and time management skills. Possesses strong technical aptitude for designing and implementing software solutions. Experience with modern application development frameworks
Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations. Deep hands-on technical expertise, excellent verbal and written communication skills. Experience with Agile software development techniques.

Preferred qualifications for this position include:
•    Masters or PhD in Machine Learning, Artificial Intelligence, Computer Science, Biomedical Engineering, or related scientific fields.
•    Experience applying AI and machine learning in production healthcare environments, highlighting an understanding of healthcare technology and its unique challenges. Experiences in AI implementation within Cancer research and practice domain preferred. 
•    Experience implementing MLOps capabilities at enterprise level, with a focus on reproducibility and ethical AI practices.
•    Skilled in advanced AI/ML techniques and frameworks, with a portfolio of complex model development projects.
•    Project experience working with cloud AI/ML services (e.g., GCP Vertex AI, AWS SageMaker, Azure ML) for large-scale model deployments.
•    Demonstrated leadership in managing complex projects, to navigate intricate project requirements and deliver successful outcomes.
•    Proficiency in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders, including clinical and research audiences.
•    Demonstrated expertise in cloud infrastructure environment and software development tools.
•    Familiarity with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
•    Mentor less-experienced team members, coupled with strong interpersonal, communication, and time management skills.
•    Deep knowledge of the healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
•    Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different project scenarios.
•    Demonstrated experience leading technical/quantitative teams in a regulated environment.
•    Demonstrated experience creating risk management files and verification/validation strategies for digital health technology products within the healthcare industry.



Compensation Detail

$$138,257.60 - $200,512.00 / year

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

40

Schedule Details

Monday - Friday, 8am - 5pm

Weekend Schedule

As needed

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.


Recruiter

Ted Keefe
Apply Now

Career Path

Discover unlimited opportunities. Your IT career may start as a Help Desk Specialist or Work Station Technician, an intern, or entry-level Analyst/Programmer and develop into a mid- or senior-level technical position. You may choose to grow laterally as a technical expert, learning and supporting many different aspects of IT services. Or you may choose to become part of the leadership team.

  • Applications
  • Business Relationship Management
  • Enterprise Infrastructure
  • Enterprise Architecture
  • Information
    Security
  • Management
  • Project Management and Systems Analysis
  • Quality
    Assurance

The Life Changers

  • When you choose an IT career with Mayo Clinic you will have an opportunity to engage with new and innovative solutions which will improve quality of life and patient outcomes. You will partner with brilliant Physicians and Scientists to help drive translational medicine in a fast-paced environment where creativity, energy, and dedication will result in success.”

    Marie Koctecki
    Senior Manager, IT Service Delivery
  • Over the span of my career, I have worked in multiple divisions across IT and have now advanced to a Service Delivery Manager role, managing a Project Management Office (PMO). The opportunities within the department of IT are vast. I have been able to gain my Project Management Professional (PMP) certification as well as my Certified Scrum Master (CSM) certification while at Mayo Clinic.”

    Betty Hutchins
    Manager, IT Service Delivery
  • I appreciate the breadth of career paths within IT and the ability to branch out and diversify my professional expertise while remaining with Mayo Clinic. The diverse backgrounds and depth of expertise of my coworkers is an attribute of Mayo’s unique culture; I enjoy the opportunity to work with so many world-renowned experts and thought leaders across a wide array of professions.”

    Samanthie Epps
    Manager, IT Speciality Systems

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All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or disability status. Learn more about "EEO is the Law." Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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